by citizen
The card backs are different, as there is Cerebus: Heroes and Cerebus: Middle-earth. However, if you have sleeves, you can mix them no problem. Just remember that:Ally = Hero
Villain = Enemy
Equipment = Artifact
Super Power = Maneuver
Super-Villain = Archenemy
Kick = Valor
Punch = Courage
Weakness = Corruption
The best way to mix the sets is by card type. Try:
DC: Equipment, Heroes, Locations, Super Heroes
LOTR: Enemies, Maneuvers, Fortunes, Archenemies
That way you won't dilute the set-specific combos.