by GeekJock
Denial of your opponents depends highly on who your opponent is.If your opponent is Flash, then grab EVERY draw card you see unless you can take out a SV. There aren't all that many draw cards and his ability is scary when it gets going.
Superman and Batman you can sort of deny but there are tons of equipment and tons of super powers. So only deny if it benefits you as well, meaning if those equip are the good ones for all, same with SPs.
WW is a sort of mix of the 2 categories above. If there is only one (Villain) on the board and it's cheap to deny then it's likely worth it, just like flash, even one activation of WW's ability is worth it to deny.
Other characters you simply cannot waste your time denying, like Vs GL, MMH and Aqua. They can trigger on too many things to deny. So just play smart and play to your strengths rather then to try and hurt them.
Hope that helps.